The orthogonal to two vectors is not a line but a plane.
What about the orthogonal to three vectors?
Surely in 4D, three different vectors can determine a fourth vector. There may be more than one way to do it, but since the 4D universe doesn't exist, we can just pick one at random.
Physical constants are pretty much irrelevant for this kind of thing. As long as the units are consistent, we should be fine.
We can keep the electric field pretty much as it is. Some particles are electric monopoles with a positive or negative charge. Opposite charges attract, same repel, e.t.c. The only difference is the inverse cube law.
A moving charge still makes a current, and concepts like voltage, power, and resistance are all the same.
I think my point about the photon still applies. Each field oscillates in a different direction, each perpendicular to the motion of the photon. So we should have three different types of EM field in 4D.
Now we have to decide whether magnetism and the other field (do you think tetric or tetratic field is too unimaginative?), will come in monopoles or dipoles. For some reason I find it easier to visualise two dipole fields.
Magnetic and Tetric flux will be the field strength * volume, instead of area.
How much of the above do you think is valid? Eventually we might have to define things like "hypercurl", or something. The maths is a bit too advanced for me just yet, but I think I can work something out just using basic physics concepts.