Hmm, airfoil.
If we could come up with a workable 4D airfoil, then this would work: you'd just attach several elongated airfoils around the rotor and you're good to go. You'd then need two perpendicular propellors in order to maintain thrust in the right orientation. Can this work? Maybe. But it depends on whether it's possible to design a 4D airfoil that does the job.
Making the (big) assumption that we could just extrude a 3D airfoil into 4D, we'd have a sort of cube-like blade extending in 2 directions and having an airfoil cross-section. WLOG, we could imagine starting with two cubes, displaced in the 4th direction from each other, and consider one cube as the "top" and the other the "bottom". Assume the flight direction is along the +Z axis. Then the +Z half of the top cube would have larger curvature into 4D, being the leading edge of the airfoil, and would ease back towards the bottom cube as you go along the -Z direction. If we use perspective projection such that +W is closer to the 4D viewpoint (and appears larger) and -W is farther (appears smaller), then the top cube would look like it's bulging outwards in its upper half, and narrows down as you go down to the bottom face.
In order to maintain lift, this airfoil needs to extend in 2 directions. So presumably we could attach say 3 of these cube pairs around some point, oriented such that their forward directions lie along some circle around the origin. This would leave 30° gaps between each cube pair. Suppose this circle lies along the XZ plane. So the first blade would point in +Z, the second blade in a combination of +X and -Z, and the third a combination of -X and -Z. As they rotate around the rotor at the origin, they would generate lift in the +W direction. There would be angular momentum in the XZ plane. Since the Y direction is not constrained in any way by this setup, there's a possibility that the aircraft might rotate in a plane involving the Y axis. Presumably we'd need a second rotor, oriented in the YZ plane. That rotation would also provide lift along +W, but would have angular momentum in the YZ plane. Together, the respective angular momentums
should prevent the aircraft from rotating as it flies.
(Though interestingly, now that I think of it, even if the helicopter were to "roll" in this way it'd still face forward, the rotation would be completely in the lateral dimensions and wouldn't affect the direction of flight or the direction of lift. It'd be extremely confusing for the pilot to maneuver, though.

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In any case, the main potential issue here would be the size of the blades, which must span a 2D area in order to provide sufficient lift. This would make them very bulky, and potentially add too much weight to the aircraft. Also, we may potentially need
four propellors: two pairs that cancel out the other's angular momentum in their respective planes of rotation. Could be either four main propellers, or two large mains and two on the tail fins, like in 3D.